Macrophage morphological plasticity and migration is Rac signalling and MMP9 dependant
Abstract In vitro, depending on extracellular matrix (ECM) architecture, macrophages migrate either in amoeboid or mesenchymal mode; while the first is a general trait of leukocytes, the latter is associated with tissue remodelling via Matrix Metalloproteinases (MMPs).To assess whether these stereotyped migrations could be also observed in a Course